Products

Presentation

Reducid^™ 20 Tablet: Each tablet contains Famotidine USP 20 mg.

Reducid^™ 40 Tablet: Each tablet contains Famotidine USP 40 mg.

Reducid^™ Powder for Suspension: After reconstitution each 5 ml suspension contains Famotidine USP 40 mg.

Description

Famotidine is a H2 receptor antagonist. By inhibiting H2 receptor, Famotidine inhibits the secretion of gastric acid, reducing both the volume of the acid and pepsin content of the secretion. Famotidine has a relatively long duration of action and a single dose effectively suppresses gastric acid secretion for twelve hours.

Indications

Famotidine is indicated in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease, acute stress ulcer and Zollinger-Ellison syndrome. It is also indicated in acute gastritis, chronic gastritis in acute exacerbation stage.

Dosage & Administration

Tablet:

• For gastric ulcer, duodenal ulcer, anastomotic ulcer, upper gastro-intestinal hemorrhage, reflux esophagitis and Zollinger-Ellison syndrome: Usual dose for adults: Famotidine 20 mg twice daily (after breakfast and after supper before bed time) or Famotidine 40 mg can be administered orally once daily at bed time.
• For the treatment of acute gastritis, chronic gastritis in acute exacerbation stage: Usual dosage for adults is Famotidine 20 mg orally twice a day (after breakfast and after supper before bed time). Also Famotidine 40 mg can be orally administered once a day (before bed time), dosage should be adjusted according to age and symptoms. Most ulcer patients heal within 4-8 weeks. For maintenance therapy the recommended oral dose is 20 mg once daily. Or, as directed by the registered physician.

• < 1 year of age: 0.5 mg/kg/dose of famotidine oral suspension up to 8 weeks once daily in patients
• Age 3 to 11 months: 0.5 mg/kg/dose twice daily up to 8 weeks
• Age 1 to 2 months: 0.5 mg/kg/dose once daily up to 8 weeks
• Neonates: 0.5 mg/kg/dose maximum once daily up to 8 weeks

• Gastroesophageal Reflux Disease(GERD):1.0 mg/kg/day p.o. divided b.i.d. up to 40 mg b.i.d.
• Duodenal ulcer: 0.5 mg/kg/day p.o. at bedtime or divided b.i.d. up to 40mg/day.
• Peptic ulcer: 0.5 mg/kg/day p.o. at bedtime or divided b.i.d. up to 40 mg/day.
• Maintenance therapy: 40 mg daily at night.
• Reflux esophagitis: 2 mg/kg/day
• Zollinger- Ellison Syndrome: 40 mg 3 times daily

Side Effects

Famotidine is indicated in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease, acute stress ulcer and Zollinger-Ellison syndrome. It is also indicated in acute gastritis, chronic gastritis in acute exacerbation stage.

Precautions

CNS adverse effects have been reported in patients with moderate and severe renal insufficiency, longer intervals between doses or lower doses may need to be used in patients with moderate creatinine clearance.

Commercial Pack

Reducid^™ 20 Tablet: Each box contains 5 blister strips of 10 tablets.
Reducid^™ 40 Tablet: Each box contains 5 blister strips of 10 tablets.
Reducid^™ Powder for Suspension: Each bottle contains dry powder for reconstituting 50 ml suspension with a measuring cup & a dropper.