Spusoft(Erdosteine)
Therapeutic Group: Mucolytic drug
Presentation
Spusoft Capsule: Each capsule contains Erdosteine INN 300 mg
Spusoft Powder for Suspension: After reconstitution each 5 ml suspension contains Erdosteine INN 175 mg
Description
Erdosteine is a mucolytic drug. It is a prodrug and it becomes active after metabolism. It acts by reducing the viscosity of mucus. In addition, it has asignificant antioxidant action and it inhibits bacterial adhesion to epithelial cells.
Indications
Erdosteine is a mucolytic drug used in the treatment of acute and chronic respiratory diseases. It also improves the symptoms associated with short episodes of chronic
bronchitis.
Dosage & Administration
Elderly patients and adults above 18 years: 1 capsule 2 times daily. Suspension: 10 ml 2 times daily.
Children (from 2 years of age):
| Body weight (kg) | Dose |
| 15 - <20 kg | 5 ml 2 times daily |
| 20 - 30 kg | 5 ml 3 times daily |
| >30 kg | 10 ml 2 times daily |
The maximum duration of therapy is 10 days.
Side Effects
Common side effect is epigastric pain. Other side effects include headache, cold, difficulty in breathing, taste alterations, nausea, vomiting, diarrhea, angioedema and other skin allergic reactions
Precautions
It should be used with caution in mild liver failure. In that case, should not exceed a dose of 300 mg per day
Use in Pregnancy & Lactation
The use of Erdosteine in pregnant or breast-feeding women is not recommended
Storage
Do not store above 30 0C. Keep away from light and out of the reach of children
Commercial Pack
Spusoft capsule: Each box contains 2 blister strips of 10 capsules
Spusoft Powder for Suspension: Each box contains one bottle containing dry powder for reconstituting 60 ml suspension and a measuring cup.