Helmiban DS Vet(Albendazole )
Therapeutic Group: Anthelmintic
Presentation
Helmiban DS Vet bolus: Each bolus contains Albendazole USP 1200 mg.
Description
Albendazole is a member of the Benzimidazole group of anthelmintic agents which is an ideal broad spectrum anthelmintic. Albendazole inhibits polymerization of tubulin causes loss of cytoplasmic microtubules that leads to impaired uptake of glucose, depletes glycogen stores, degenerative change in the endoplasmic reticulum and mitochondria & decrease production of ATP. It also inhibits the enzyme fumarate reductase which is a co-enzyme in many cellular oxidation-reduction reactions result no energy production and immobilization and death of parasites.
Indications
Albendazoleis used as anthelmintic against most nematodes and cestodes. It is effective against these gastro-intestinal parasites Bunostomum, Chabertia, Cooperia, Haemonchus, Ostertagia, Nematodirus, Strongyloides, Dictyocaulusviviparus, Monieziaexpansa, Liver flukes and Paramphistomes. It is also effective against different types of worms, lung flukes and lung nematodes.
Dosage & Administration
To keep animal free from helminths animal should be treated at 3 months interval.
Cattle & Buffalo: 7.5-10 mg/kg body weight or 14 bolus for 30-40 kg body weight, 12 bolus for 60-80 kg body weight & 1 boli for 120-160 kg body weight.
Goat & Sheep: 5-7.5 mg/kg body weight or 112 bolus for 13-20 kg body weight & 1 6 bolus for 27-40 kg body weight.
Dog & Cat: 15 mg/kg body weight or 18 bolus for 8-10 kg body weight & 14 bolus for 16-20 kg body weight.
Or as directed by the registered Veterinarian.
Side Effects
Albendazole is time tested and clinically proven well tolerated drug. Established wide safety margin than any other anthelmentic due to greater selective affinity for parasitic b-tubulin than for animal tissues. However, in some cases nausea and vomiting may occur.
Precautions
Before using Albendazole inform the registered Veterinarian that your animals are not allergic to it; or to other benzimidazole anthelmintic drugs (e.g. Mebendazole).
Use in Pregnancy & Lactation
Albendazole should not use first 45 days of pregnancy of cow. Do not administer to ewes or does during the first 30 days of pregnancy. Sufficient data on use during lactation is not available. Therefore breast feeding should be discontinued during and for a minimum of 5 days after treatment.
Drug Interaction
Cimetidine, Praziquantel and Dexamethasone have been reported to increase the plasma levels of Albendazole active metabolite.
Over Dose
If poisoning or excessive overdosageis suspected, it is recommended for vomiting be induction or gastric lavage and such symptomatic supportive therapy to be administered.
Withdrawal Period
Milk: 2.5-3 days
Meat: Cattle: 14 days; Sheep & goat: 4 days
Storage
Do not store above 30 degree centigrade. Keep away from light and out of the reach of children.
Commercial Pack
Helmiban DS Vet bolus: Each box contains 10 blisters of 2 boli.