Simethicone is an effective antiflatulent. The clinical use of Simethicone is based on its antifoaming properties. The defoaming action of Simethicone relieves flatulence by dispersing and preventing the formation of mucus-surrounded gas pockets in the GI tract. It acts in the stomach and intestines to change the surface tension of gas bubbles, enabling them to coalesce; thus gas is freed and eliminated more easily by belching or passing flatus.

Lefoam drops is indicated in the following cases-

-For treating symptoms of infantile colic.

-For relief of the painful symptoms of excess gas in the digestive tract, including upper GI bloating, pressure, fullness or stuffed feeling.

-As an adjunct in the treatment of post-operative gaseous distension, air swallowing, functional dyspepsia, peptic ulcer, spastic or irritable colon.

-Prior to gastroscopy to enhance visualization and prior to radiography of the intestine to reduce gas shadows.

-In the management of accidental ingestion of foaming detergents.

Lefoam drops should be taken after meals and at bedtime or as directed by the physician. Shake the bottle well before use.
Children younger than 2 years of age: 20 mg (0.3 ml Lefoam drops) 4 times daily up to 240 mg/day (3.6 ml Lefoam drops).
Children 2 to12 years of age: 40 mg (0.6 ml Lefoam drops) 4 times daily.
Adults and children older than 12 years of age: 40 to 80 mg (0.6 to 1.2 ml Lefoam drops) 4 times daily up to 500 mg/day (7.5 ml Lefoam drops).

Simethicone is physiologically inert and no adverse effect has been reported after oral ingestion.

More than 12 doses per day should not be used, except under the advice and supervision of a physician. Keep the medicine out of the reach of children.

There is no information about the contraindication of Simethicone.

Pregnancy: No data are available to suggest any harmful effects in pregnancy.
Lactation: Excretion of Simethicone in the breast milk has not been established, but would be most unlikely.

Overdosage of Simethicone is not expected to cause clinically important effects and no specific treatment is indicated.

Lefoam Drops: Bottle containing 15 ml drops with a plastic dropper.