Seasonix
Levocetirizine Dihydrochloride film-coated Tablet

Presentation
Seasonix : Each film-coated tablet contains Levocetirizine Dihydrochloride INN 5 mg.

Description
Seasonix tablet is a preparation of Levocetirizine Dihydrochloride. Levocetirizine is the active (levo) isomer of Cetirizine. It is a new highly effective and well-tolerated non-sedating antihistamine with potent antiallergic properties. It has a two-fold higher affinity for H1-receptors than Cetirizine. Levocetirizine has a rapid and long-lasting action, allowing once-a-day administration.

Indications and Uses
Treatment of symptoms associated with allergic conditions such as seasonal allergic rhinitis, perennial allergic rhinitis and chronic idiopathic urticaria.

Dosage and Administration
Adults & children over 6 years of age: One Seasonix tablet (Levocetirizine Dihydrochloride 5 mg) once daily.
Patients with renal impairment: The recommended dose in patients with moderate renal impairment is one Seasonix tablet (Levocetirizine Dihydrochloride 5 mg) every two days. In those with severe renal impairment, the dose interval should be increased to every three days. Patients with end-stage renal disease should not be given Levocetirizine.

Side-effects
Generally Levocetirizine is well tolerated. However, a few side effects like headache, dry mouth, fatigue and skin rash have been reported rarely.

Contraindications
Seasonix is contraindicated in patients who are hypersensitive to this medication or to any of its ingredients.

Use in pregnancy and lactation
Pregnancy: The safety of Levocetirizine in pregnancy has not been established. Therefore, it should be used with caution during pregnancy and only if the benefits to the mother outweigh any risks to the fetus.
Lactation: Levocetirizine passes into breast milk. So, it should be used with caution in nursing mothers and only if the expected benefit to the mother is greater than the possible risk to the nursing infant.

Pediatric use
Not recommended for use in children less than 6 years of age.

Drug interaction
No clinically important drug interactions have been reported.

Overdosage
No clinically relevant adverse events have been reported in case of overdosage. However, in the event of overdosage, symptomatic and supportive treatment is recommended.

Commercial pack
Seasonix : Each box contains 10 blister strips of 10 tablets.