Fusiderm
Antibiotic/Corticosteroid cream

Presentation
Each gram contains:
Fusidic acid BP 20 mg
Hydrocortisone acetate BP 10 mg

Description
Fusiderm cream combines the potent topical antibacterial action of fusidic acid with the anti-inflammatory and anti-pruritic effects of hydrocortisone.
When applied topically, fusidic acid is effective against Staphylococci, Streptococci, Corynebacteria, Neisseria and certain Clostridia and Bacteroides. The antibacterial activity of fusidic acid is not diminished in the presence of hydrocortisone.

Indications
Fusiderm is indicated in eczema and dermatitis with secondary infections including atopic dermatitis, allergic and seborrhoeic dermatitis and primary irritant dermatitis.

Dosage and Administrations
Uncovered lesions: 3-4 times daily applications
Covered lesions: Less frequent application may be adequate.

Side effects
Hypersensitivity has rarely been encountered. As with other topical steroids, prolonged and intensive treatment may cause local atrophic changes of the skin, such as striae, thinning and dilatation of the superficial blood vessels, particularly when occlusive dressing is used or when skin folds are involved. Systemic absorption, sufficient to produce adrenal suppression, can occur with prolonged or extensive use, especially when napkin is used. Infants and children are particularly at risk. Caution should be exercised if a topical steroid is used near the eye. Glaucoma might be the result if the preparation enters the eye.

Contraindications
Topical hydrocortisone is contraindicated in viral, tuberculosis and fungal skin infections. Hypersensitivity to any of the components.

Precautions
Long-term continuous therapy should be avoided, particularly in the face, on flexures, and intertrigenous areas, and in infants and children.

Use in Pregnancy and Lactation
Fusidic acid and Hydrocortisone should not be used in pregnancy. Both of them have been detected in the breast milk, so nursing mothers are advised not to use the drug.

Commercial pack
Fusiderm: Tube containing 10 gm of Fusidic acid and Hydrocortisone acetate cream.