Iriban
Mebeverine Hydrochloride

Presentation
Iriban tablet: Each tablet contains Mebeverine Hydrochloride BP 135 mg.

Description
Iriban is a musculotropic antispasmodic agent used to relieve cramps or spasms of the stomach and intestines (gut). It is particularly useful in treating irritable bowel syndrome (IBS) and similar conditions. It works by relaxing the muscles and helping to restore the normal movement of the gut.

Indications and Uses
Iriban is indicated
For the symptomatic treatment of irritable bowel syndrome (IBS)

Other conditions include:

Chronic irritable colon

Spastic constipation

Mucous colitis

Colicky abdominal pain

Persistent non-specific diarrhoea

Contraindications
Not known

Dosage And Administration
Adults, elderly and children over 10 years: One tablet three times a day.

Iriban is most effective when taken 20 minutes before meals. After a several weeks when the desired effect has been obtained, the dosage may be gradually reduced.

*Missed dose: If a dose of this medicine is missed that should be taken as soon as possible. However, if it is almost time for the next dose, then skip the missed dose and the regular dosing schedule should be maintained. Dose should not be doubled at the same time to compensate the missed dose.

Precautions
Caution should be exercised in porphyria or allergic reaction to this or any other medicine.

Side Effects
Generally Mebeverine is well tolerated. However, few side-effects like skin rash, urticaria and angioedema may appear.

Use in pregnancy & lactation
No teratogenicity has been shown in animal experiments. However, the usual precautions concerning the administration of any drug during pregnancy should be exercised.

Mebeverine does not excrete in the breast milk after administering the therapeutic dose.

Use in children
Mebeverine is not recommended in children under 10 years.

Overdosage
On theoretical grounds it may be predicted that CNS excitability will occur in case of overdosage. No specific antidote is known: gastric lavage and symptomatic treatment is recommended.

Commercial Pack
Iriban tablet: Each box contains 5 blister strips of 10 tablets.;